Home＞Research＞Team＞Molecular-Recogunition Structure Analysis Team＞Outline of research
３D drug design team
Outline of research
Observation of protein-drug interaction by using our original NMR and other experimental/theoretical method
We have analyzed protein-protein interaction and protein-drug interaction by using the NMR experiment with the original protein expression method and original NMR method. We can reconstruct the 3D-coordinates models of protein-protein/protein-drug complex structures by our original combination method of the NMR and theoretical simulation methods.
Applications
・Validation of screening hit compounds
・Modeling of protein-drug complex structure
・Lead generation by quantitative structure activity relationship(QSAR)